A direct loop: glucose and insulin
Blood glucose
normal
range
glucose into blood
Humoral stimulus –
sensed directly
insulin into blood
Liver
Muscle
Fat
insulin slows to a trickle
1
Blood glucose rises
2
Pancreatic beta cells
detect it
3
Insulin released
4
Cells take up glucose
5
Glucose falls →
insulin release falls
–
negative feedback
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