Endochondral ossification
The future bone
Hyaline cartilage
Perichondrium
Ends left bare: joints will form here
1
Cartilage model
Bone collar
Periosteum
Calcified cartilage
2
Bone collar;
cartilage calcifies
Primary ossification centre
Blood vessel
3
Primary ossification
centre
Medullary cavity
Appositional growth
Spongy bone
4
Medullary cavity forms
Secondary ossification centre
Secondary ossification centre
5
Secondary ossification
centres
Epiphyseal plate
Epiphyseal plate
Articular cartilage
Articular cartilage
6
Plate and joint
surfaces remain
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